Hypertension in Low- and Middle-Income Countries
Low- and middle-income countries (LMICs) have been witnessing a significant shift toward raised blood pressure. In LMICs, only 1 in 3 are aware of the...
Caveolin3 Stabilizes McT1-Mediated Lactate/Proton Transport in Cardiomyocytes
The aim was to identify differential CAV1 versus CAV3 protein interactions and to define the molecular basis of cardiacCAV3 loss-of-function. McT1 rep...
Molecular Mechanisms of Diaphragm Myopathy in Humans With Severe Heart Failure
Diaphragm weakness impairs quality of life, exercise capacity, and survival in patients with chronic heart failure (CHF) and reduced left ventricular...
Recent Randomized Trials of Antithrombotic Therapy for Patients With COVID-19: JACC State-of-the-Art Review
Endothelial injury and microvascular/macrovascular thrombosis are common pathophysiological features of coronavirus disease-2019 (COVID-19). We search...
Deep Neural Networks Can Predict New-Onset Atrial Fibrillation From the 12-Lead ECG and Help Identify Those at Risk of Atrial Fibrillation–Related Stroke
Atrial fibrillation (AF) is associated with substantial morbidity, especially when it goes undetected. Deep neural networks were trained to predict ne...
Artificial Intelligence–Enabled Assessment of the Heart Rate Corrected QT Interval Using a Mobile Electrocardiogram Device
Heart rate–corrected QT interval (QTc) prolongation can predispose to ventricular arrhythmias and sudden cardiac death. Currently, QTc assessment and...
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