Design and Multicenter Clinical Validation of a 3-Dimensionally Printed Nasopharyngeal Swab for SARS-CoV-2 Testing
3DP swabs have been used to mitigate swab shortages during the coronavirus disease 2019 (COVID-19) pandemic. Clinical validation for diagnostic accura...
A Highly Automated Mobile Laboratory for On-site Molecular Diagnostics in the COVID-19 Pandemic
The mobile laboratory was equipped with a 6-axis robot arm for automated oropharyngeal swab specimen collection. The virus in the collected specimen w...
Impact of serological and PCR testing requirements on the selection of COVID-19 convalescent plasma donors
Convalescent plasma is undergoing randomized trials as a potential therapeutic option for COVID-19 infection. Clearance for donation required successf...
Analytical sensitivity and clinical performance of a triplex RT-qPCR assay using CDC N1, N2, and RP targets for SARS-CoV-2 diagnosis
The nCoV19 CDC includes two targets for detecting SARS-CoV-2 and an RNaseP (RP) and an RNA extraction quality control. Several RT-qPCR kits are availa...
SARS-CoV-2 screening of asymptomatic women admitted for delivery must be performed with a combination of microbiological techniques: an observational study
Authors: 9 women were positive for SARS-CoV-2 in nasopharyngeal samples and 13 presented positive specific antibodies of the coronavirus. Vaginal deli...
Reverse-transcriptase polymerase chain reaction versus chest computed tomography for detecting early symptoms of COVID-19. A diagnostic accuracy systematic review and meta-analysis
Comes during the first week of its symptoms during the pandemic. Some studies have demonstrated a significant number of false-negative RT-PCR tests. I...
Prolonged persistence of PCR-detectable virus during an outbreak of SARS-CoV-2 in an inpatient geriatric psychiatry unit in King County, Washington
10 patients and 7 staff members with SARS-CoV-2 infection. Thirty percent of patients remained asymptomatic over the course of infection. Cough and fe...
Kinetics of Viral Clearance and Antibody Production Across Age Groups in Children with Severe Acute Respiratory Syndrome Coronavirus 2 Infection
The study looked at children tested for SARS-CoV-2 by reverse transcription (RT) polymerase chain reaction (PCR) and immunoglobulin G antibody. Median...
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