Remdesivir for the treatment of COVID-19: A systematic review and meta-analysis of randomized controlled trials
Remdesivir was among the first antiviral therapies to be tested in RCTs for COVID-19. At a follow-up of 28-29 days, the use of remdesivir was not asso...
Ozone therapy for patients with COVID-19 pneumonia: Preliminary report of a prospective case-control study
The study involved 18 patients with COVID-19 infection (laboratory-confirmed) severe pneumonia. Each treatment involved the administration of whole bl...
Helmet continuous positive airway pressure versus high-flow nasal cannula in COVID-19: a pragmatic randomized clinical trial (COVID HELMET)
Oxygen delivery by helmet continuous positive airway pressure (CPAP) is a feasible option. It enables a higher positive positive end-expiratory press...
Demographic risk factors for COVID-19 infection, severity, ICU admission and death: a meta-analysis of 59 studies
Age and sex are associated with the risk of COVID-19 in different severity stages ranging from infection to death. Patients aged 70 years and above ha...
Systematic review on current antiviral therapy in COVID-19 pandemic
There are several attempts to find an effective antiviral drug against the COVID-19. Up to 5-10% of patients may have severe, life-threatening events...
Acute kidney injury and renal replacement therapy in COVID-19 patients: A systematic review and meta-analysis
A meta-analysis conducted to gain clarity regarding AKI incidence and renal replacement therapy (RRT) use in COVID-19 patients. We searched for COVID...
Circulating Levels of Interleukin-6 and Interleukin-10, But Not Tumor Necrosis Factor-Alpha, as Potential Biomarkers of Severity and Mortality for COVID-19: Systematic Review with Meta-analysis
Cytokine storm is an uncontrolled overproduction of inflammatory cytokines. It is a major pathological feature of acute respiratory distress syndromes...
Factors associated with psychological distress during the coronavirus disease 2019 (COVID-19) pandemic on the predominantly general population: A systematic review and meta-analysis
The Coronavirus Disease 2019 (COVID-19) outbreak has escalated the burden of psychological distress. We searched databases for studies that reported f...