The dysregulated innate immune response in severe COVID-19 pneumonia that could drive poorer outcome
The coronavirus disease 2019 (COVID-19) has peculiar characteristics and outcomes, suggesting a unique immunopathogenesis. 19 patients had lower level...
Clinical manifestations and outcomes of COVID-19 in the paediatric population: a systematic review
Coronavirus disease 2019 (COVID-19) has affected hundreds of thousands of people. We aim to report the distribution of cases, prevalence, and clinical...
Infection and mortality of healthcare workers worldwide from COVID-19: a systematic review
To estimate COVID-19 infections and deaths in healthcare workers (HCWs) from a global perspective during the early phases of the pandemic. Two paralle...
Targeting the NO-cGMP-PDE5 pathway in COVID-19 infection. The DEDALO project
A pandemic outbreak of COVID-19 has been sweeping the world since December. Some clinical trials are testing biological drugs to limit immune system d...
[COVID-19 in orthopedics]
This is a systematic literature review for COVID-19, SARS-CoV-2 with Orthopedic and Spine Surgery relevance. It is to determine in Orthopedic Surgery...
Convalescent plasma may be a possible treatment for COVID-19: A systematic review Convalescent plasma may be a possible treatment for COVID-19: A systematic review
The coronavirus disease 2019 (COVID-19) pandemic has spread globally. Convalescent plasma immunotherapy was an effective method for fighting similar v...
Venous thromboembolism in patients with COVID-19: Systematic review and meta-analysis
Venous thromboembolism (VTE) may complicate the course of Coronavirus Disease 2019 (COVID-19) Study looked for studies that evaluated the incidence of...
Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults
Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19) remain elusive. Among them, convalescent plasma administered to ho...
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