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Grand challenges for medical physics in radiation oncology
Medical physicists are key players in the clinical and scientific radiation oncology context. They have unique skill sets, flexibility, clinical invol...
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Surgery for malignant pleural mesothelioma after radiotherapy (SMART): final results from a single-centre, phase 2 trial
The SMART protocol consists of a short accelerated course of radiotherapy followed by extrapleural pneumonectomy. Patients received 25 Gy in five dail...
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Radiation Therapy Oncology Group consensus panel guidelines for the delineation of the clinical target volume in the postoperative treatment of pancreatic head cancer
The postoperative abdomen has been a difficult area for effective radiotherapy. These new guidelines will help physicians create fields that better en...
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Postmastectomy Radiotherapy: An American Society of Clinical Oncology, American Society for Radiation Oncology, and Society of Surgical Oncology Focused Guideline Update
PMRT reduces the risks of locoregional failure (LRF), any recurrence, and breast cancer mortality. Some patients are likely to have such a low risk of...
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Evidence-based benchmarks for use of cancer surgery in high-income countries: a population-based analysis
Surgical treatment was indicated in 58% of newly diagnosed patients with cancer in Australia in 2014 at least once during the course of their treatmen...
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Effect of denosumab on osteolytic lesion activity after total hip arthroplasty: a single-centre, randomised, double-blind, placebo-controlled, proof of concept trial
Osteolysis causes recurrent pain and disability after total hip arthroplasty. We investigated the effect of the human monoclonal antibody denosumab on...
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Genetic risk, incident gastric cancer, and healthy lifestyle: a meta-analysis of genome-wide association studies and prospective cohort study
New risk model to assess the benefits of adhering to a healthy lifestyle in individuals with a high genetic risk. The polygenic risk score derived fro...
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Preoperative radiotherapy plus surgery versus surgery alone for patients with primary retroperitoneal sarcoma (EORTC-62092: STRASS): a multicentre, open-label, randomised, phase 3 trial
EORTC-62092 is an open-label, randomized, phase 3 study done in 31 research institutions, hospitals, and cancer centers in 13 countries in Europe and...