Impact of the KCNQ2/3 Channel Opener Ezogabine on Reward Circuit Activity and Clinical Symptoms in Depression: Results From a Randomized Controlled Trial
This is the first randomized placebo-controlled trial to test the effect of the KCQ2-2 positive modulator ezogabine on reward circuit activity and out...
Effects of dapagliflozin on major adverse kidney and cardiovascular events in patients with diabetic and non-diabetic chronic kidney disease: a prespecified analysis from the DAPA-CKD trial
The multicentre, double-blind, placebo-controlled, randomized trial was done at 386 study sites in 21 countries. The relative risk reduction for the p...
The effect of vitamin D supplementation on acute respiratory tract infection in older Australian adults: an analysis of data from the D-Health Trial
We used data from the D-Health Trial, a randomized, double-blind, placebo-controlled trial of vitamin D supplementation. Vitamin D supplementation did...
Short-term outcomes of complete mesocolic excision versus D2 dissection in patients undergoing laparoscopic colectomy for right colon cancer (RELARC): a randomised, controlled, phase 3, superiority trial
This randomized, controlled, phase 3, superiority, trial was done at 17 hospitals in nine provinces of China. Eligible patients were aged 18–75 years...