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Development of SARS-CoV-2 vaccines
The coronavirus disease 2019 (COVID-19) pandemic has posed significant challenges globally. This review aimed to identify and describe possible vaccin...
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Variability of cycle threshold values in an external quality assessment scheme for detection of the SARS-CoV-2 virus genome by RT-PCR
Results of SARS-CoV-2 specific real-time reverse transcription (RT) are used for initial diagnosis and follow-up of Covid-19 patients and asymptomatic...
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Design and Multicenter Clinical Validation of a 3-Dimensionally Printed Nasopharyngeal Swab for SARS-CoV-2 Testing
3DP swabs have been used to mitigate swab shortages during the coronavirus disease 2019 (COVID-19) pandemic. Clinical validation for diagnostic accura...
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A Highly Automated Mobile Laboratory for On-site Molecular Diagnostics in the COVID-19 Pandemic
The mobile laboratory was equipped with a 6-axis robot arm for automated oropharyngeal swab specimen collection. The virus in the collected specimen w...
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Impact of serological and PCR testing requirements on the selection of COVID-19 convalescent plasma donors
Convalescent plasma is undergoing randomized trials as a potential therapeutic option for COVID-19 infection. Clearance for donation required successf...
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Analytical sensitivity and clinical performance of a triplex RT-qPCR assay using CDC N1, N2, and RP targets for SARS-CoV-2 diagnosis
The nCoV19 CDC includes two targets for detecting SARS-CoV-2 and an RNaseP (RP) and an RNA extraction quality control. Several RT-qPCR kits are availa...
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SARS-CoV-2 screening of asymptomatic women admitted for delivery must be performed with a combination of microbiological techniques: an observational study
Authors: 9 women were positive for SARS-CoV-2 in nasopharyngeal samples and 13 presented positive specific antibodies of the coronavirus. Vaginal deli...
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Reverse-transcriptase polymerase chain reaction versus chest computed tomography for detecting early symptoms of COVID-19. A diagnostic accuracy systematic review and meta-analysis
Comes during the first week of its symptoms during the pandemic. Some studies have demonstrated a significant number of false-negative RT-PCR tests. I...