Development of SARS-CoV-2 vaccines

The coronavirus disease 2019 (COVID-19) pandemic has posed significant challenges globally. This review aimed to identify and describe possible vaccin...

Variability of cycle threshold values in an external quality assessment scheme for detection of the SARS-CoV-2 virus genome by RT-PCR

Results of SARS-CoV-2 specific real-time reverse transcription (RT) are used for initial diagnosis and follow-up of Covid-19 patients and asymptomatic...

Design and Multicenter Clinical Validation of a 3-Dimensionally Printed Nasopharyngeal Swab for SARS-CoV-2 Testing

3DP swabs have been used to mitigate swab shortages during the coronavirus disease 2019 (COVID-19) pandemic. Clinical validation for diagnostic accura...

A Highly Automated Mobile Laboratory for On-site Molecular Diagnostics in the COVID-19 Pandemic

The mobile laboratory was equipped with a 6-axis robot arm for automated oropharyngeal swab specimen collection. The virus in the collected specimen w...

Impact of serological and PCR testing requirements on the selection of COVID-19 convalescent plasma donors

Convalescent plasma is undergoing randomized trials as a potential therapeutic option for COVID-19 infection. Clearance for donation required successf...

Analytical sensitivity and clinical performance of a triplex RT-qPCR assay using CDC N1, N2, and RP targets for SARS-CoV-2 diagnosis

The nCoV19 CDC includes two targets for detecting SARS-CoV-2 and an RNaseP (RP) and an RNA extraction quality control. Several RT-qPCR kits are availa...

SARS-CoV-2 screening of asymptomatic women admitted for delivery must be performed with a combination of microbiological techniques: an observational study

Authors: 9 women were positive for SARS-CoV-2 in nasopharyngeal samples and 13 presented positive specific antibodies of the coronavirus. Vaginal deli...

Reverse-transcriptase polymerase chain reaction versus chest computed tomography for detecting early symptoms of COVID-19. A diagnostic accuracy systematic review and meta-analysis

Comes during the first week of its symptoms during the pandemic. Some studies have demonstrated a significant number of false-negative RT-PCR tests. I...

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