Smoking, Genetic Predisposition, and Colorectal Cancer Risk

Smoking and genetic predisposition are established risk factors for colorectal cancer. A PRS above the 90th percentile was significantly associated wi...

Tazemetostat for patients with relapsed or refractory follicular lymphoma: an open-label, single-arm, multicentre, phase 2 trial

Activating mutations of EZH2, an epigenetic regulator, are present in 20% of follicular lymphoma patients. Tazemetostat monotherapy showed clinically...

Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study

The genetic basis of variation in the progression of primary tauopathies has not been determined. We aimed to identify genetic determinants of surviva...