Tranexamic acid in patients with intracerebral haemorrhage (STOP-AUST): a multicentre, randomised, placebo-controlled, phase 2 trial
Tranexamic acid decreases haemorrhage in conditions such as acute trauma and menorrhoea. Between March 1, 2013, and Aug 13, 2019, we enrolled and rand...
Long-term safety and efficacy of patisiran for hereditary transthyretin-mediated amyloidosis with polyneuropathy: 12-month results of an open-label extension study
Hereditary transthyretin-mediated amyloidosis is a rare, inherited, progressive disease caused by mutations in the tranStHyretin (TTR) gene. The globa...
Safety and efficacy of prednisone versus placebo in short-term prevention of episodic cluster headache: a multicentre, double-blind, randomised controlled trial
Prednisone is commonly used for short-term therapy of episodic cluster headaches before preventive medication such as verapamil becomes effective. We...
Safety and efficacy of riluzole in patients undergoing decompressive surgery for degenerative cervical myelopathy (CSM-Protect): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial
Degenerative cervical myelopathy is the most common form of non-traumatic spinal cord injury. This multicentre, double-blind, placebo-controlled, rand...
Comparison of eight prehospital stroke scales to detect intracranial large-vessel occlusion in suspected stroke (PRESTO): a prospective observational study
Prehospital stroke scales have been proposed to select patients with large-vessel occlusion for direct transport. The NIHSS as assessed by a clinician...
Detection of α-synuclein in CSF by RT-QuIC in patients with isolated rapid-eye-movement sleep behaviour disorder: a longitudinal observational study
Isolated rapid-eye-movement (REM) sleep behavior disorder (IRBD) can be part of the prodromal stage of the alpha-synucleinopathies Parkinson's disease...
Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial
Tilavonemab (ABBV-8E12) is a monoclonal antibody that binds to the N-terminus of human tau. Progressive supranuclear palsy is a neurodegenerative diso...
MRI Brain Templates of the Male Yucatan Minipig
The pig is growing in popularity as an experimental animal because its gyrencephalic brain is similar to humans. Currently, however, there is a lack o...
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