Role of the Peroxisome Proliferator Activated Receptors in Hypertension

Nuclear receptors represent a large family of ligand-activated transcription factors which sense the physiological environment. We will focus on the P...

Efficacy and safety of setmelanotide, an MC4R agonist, in individuals with severe obesity due to LEPR or POMC deficiency: single-arm, open-label, multicentre, phase 3 trials

Melanocortin 4 receptor (MC4R) receptor plays a part in body weight regulation. Severe early-onset obesity can be caused by biallelic variants in gene...

Influence of methodological and patient factors on serum NMDAR IgG antibody detection in psychotic disorders: a meta-analysis of cross-sectional and case-control studies

Antibodies targeting the N-methyl-D-aspartate receptor (NMDAR) have been detected in patients with psychosis. It is unclear whether these antibodies a...