Ventricular fibrillation mechanism and global fibrillatory organization are determined by gap junction coupling and fibrosis pattern
Conflicting data exist supporting differing mechanisms for sustaining ventricular fibrillation. Abnormal gap junction (GJ) coupling and fibrosis are important in the initiation and maintenance of VF. The degree of fibrosis pattern and the pattern of coupling with carbenoxolone influences the mechanism sustaining VF
