Surgery for malignant pleural mesothelioma after radiotherapy (SMART): final results from a single-centre, phase 2 trial
The SMART protocol consists of a short accelerated course of radiotherapy followed by extrapleural pneumonectomy. Patients received 25 Gy in five daily fractions over 1 week to the entire ipsilateral hemithorax. 47% of patients had 30-day perioperative grade 3–4 events