Risk of hydroxychloroquine alone and in combination with azithromycin in the treatment of rheumatoid arthritis: a multinational, retrospective study
Hydroxychloroquine has received negative publicity for adverse events associated with its authorization for emergency use to treat patients with COVID-19 pneumonia. Long-term use of hydroxychloroquine appears to be associated with increased cardiovascular mortality. The addition of azithromycin appears to increase the risk of heart failure and chest pain or angina.