Faecal microbiota transplantation for recurrent Clostridioides difficile infection: An updated systematic review and meta-analysis
Faecal microbiota transplantation (FMT) is effective for recurrent Clostridioides difficile infection (CDI) However, inconsistent effect rates and uncertain evidence levels have warranted caution. We aimed to establish the evidence of FMT for recurrent CDI across different delivery methods, treatment regimens, and in comparison with standard antibiotics. The overall clinical effect week 8 following repeat FMT (24 studies, 1855 patients) was 91% (95% CI: 89-94%, I 2=53%) and 84% (80-88%) followin