Systematic review with meta-analysis: age-related malignancy detection rates at upper gastrointestinal endoscopy
Age is an important and objective risk factor for upper gastrointestinal (GI) malignancy. The accuracy of various age limits to detect upper GI malignancies is unclear. Aim of this analysis was to synthesize data on upper GI malignancy detection rates. To detect >80% of malignant cases all symptomatic patients over 40 years of age should be investigated in Africa,over 50 years of age in South America and Asia, and over 55 years of age in North America and Europe.