Effects of bisphosphonates on long-term kidney transplantation outcomes
Bisphosphonates are administered to post-transplantation patients with mineral and bone disorders. The study enrolled 3836 kidney transplant recipients treated from April 1979 to June 2016. Users had a significantly reduced risk of graft failure. Increased cumulative duration of use and higher dose above the first quartile was associated with reduced risk. Bisphosphonates may improve long-term graft survival in kidney transplant recipients.