Safety and Efficacy of the BNT162b2 mRNA Covid-19 Vaccine
Severe acute respiratory syndrome coronavirus 2 has afflicted tens of millions of people in a worldwide pandemic. Safe and effective vaccines are needed urgently. The BNT162b2 vaccine candidate encodes a prefusion stabilized membrane-anchored SARS-CoV-2 full-length spike protein. The vaccine was 95% effective in preventing Covid-19 (95% credible interval, 90.3 to 97.6). Similar vaccine efficacy was observed across subgroups defined by age, sex, race, ethnicity, baseline body-mass index, and the
