Optimal duration of fertility-sparing hormonal treatment for early-stage endometrioid endometrial cancer
To analyze oncologic outcomes of long-term fertility-sparing treatment (FST) in patients with early-stage endometrial cancer. Patients undergoing FST for presumed stage IA, grade 1 EC between 2005 and 2008 were retrospectively analyzed. Patients not achieving CR and not showing PD at 6 months of FST could continue further FST. If disease progression is excluded, 15 months of FST can be considered as the cutoff for the optimal FST duration.