Prevalence of Comorbid Asthma and Related Outcomes in COVID-19: A Systematic Review and Meta-Analysis

The impact of asthma on coronavirus disease 2019 (COVID-19) remains largely unknown. To investigate the asthma prevalence among patients with COVID-19...

The dysregulated innate immune response in severe COVID-19 pneumonia that could drive poorer outcome

The coronavirus disease 2019 (COVID-19) has peculiar characteristics and outcomes, suggesting a unique immunopathogenesis. 19 patients had lower level...

Infection and mortality of healthcare workers worldwide from COVID-19: a systematic review

To estimate COVID-19 infections and deaths in healthcare workers (HCWs) from a global perspective during the early phases of the pandemic. Two paralle...

Targeting the NO-cGMP-PDE5 pathway in COVID-19 infection. The DEDALO project

A pandemic outbreak of COVID-19 has been sweeping the world since December. Some clinical trials are testing biological drugs to limit immune system d...

[COVID-19 in orthopedics]

This is a systematic literature review for COVID-19, SARS-CoV-2 with Orthopedic and Spine Surgery relevance. It is to determine in Orthopedic Surgery...

Early High-Titer Plasma Therapy to Prevent Severe Covid-19 in Older Adults

Therapies to interrupt the progression of early coronavirus disease 2019 (Covid-19) remain elusive. Among them, convalescent plasma administered to ho...

COVID-19 and Headache Medicine: A Narrative Review of Non-Steroidal Anti-Inflammatory Drug (NSAID) and Corticosteroid Use

The use of non-steroidal anti-inflammatory drugs and corticosteroids in patients during the COVID-19 pandemic has been controversial. Evidence for or...

Why does COVID-19 kill more elderly men than women? Is there a role for testosterone?

There may be a gender predisposition to COVID-19, with men predisposed to being most severely affected, and older men accounting for most deaths. Revi...

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