Helmet continuous positive airway pressure versus high-flow nasal cannula in COVID-19: a pragmatic randomised clinical trial (COVID HELMET)

CPAP is a feasible option that enables a higher positive positive end-expiratory pressure (PEEP) We hypothesize that the use of Helmet CPAP will reduc...

The associations between fasting plasma glucose levels and mortality of COVID-19 in patients without diabetes

Coronavirus disease 2019 (COVID-19) which is novel pneumonia can rapidly progress to acute respiratory distress syndrome, septic shock, and multiple o...

Systematic Review and Meta-Analysis on the Value of Chest CT in the Diagnosis of Coronavirus Disease (COVID-19): Sol Scientiae, Illustra Nos

Methodologic quality was assessed using the Quality Assessment of Diagnostic Accuracy Studies 2 (QUADAS-2) tool. All six studies included patients at...

Factors associated with psychological distress during the coronavirus disease 2019 (COVID-19) pandemic on the predominantly general population: A systematic review and meta-analysis

The prevalence of anxiety and depression was 33% (95% CI: 28%-39%) and 30% (26%-36%) in the outbreak. One in three adults in the predominantly general...

Clinical frailty scale and mortality in COVID-19: A systematic review and dose-response meta-analysis

The National Institute for Health and Care Excellence (NICE) endorsed the clinical frailty scale (CFS) to help with decision-making. Each 1-point incr...

Safety and efficacy of convalescent plasma therapy in severely and critically ill patients with COVID-19: a systematic review with meta-analysis

More attention has been focused on the use of convalescent plasma (CP) for the treatment of SARS-CoV-2. The severely ill patients benefited more from...

Covid19 new Strains

A combination of a large asymptomatic population and the presence of more infectious variants of the virus during the second wave, which is much steep...

No benefit of hydroxychloroquine in COVID-19: Results of Systematic Review and Meta-Analysis of Randomized Controlled Trials

Coronavirus pandemic is currently a global public health emergency with no definitive treatment guidelines. We conducted a systematic review and meta-...

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