Circulating Levels of Interleukin-6 and Interleukin-10, But Not Tumor Necrosis Factor-Alpha, as Potential Biomarkers of Severity and Mortality for COVID-19: Systematic Review with Meta-analysis

Cytokine storm is a major pathological feature of acute respiratory distress syndromes. Circulating levels of IL-6 and IL-10 might have great potentia...

What is the evidence for transmission of COVID-19 by children in schools? A living systematic review

Emerging evidence suggests a lower IAR and Sars-Cov-2 positivity rate in students compared to school staff. Future prospective and adequately controll...

Characteristics of pediatric multi-system inflammatory syndrome (PMIS) associated with COVID-19: a meta-analysis and insights into pathogenesis

An outbreak of pediatric multisystem inflammation syndrome (PMIS) was observed in multiple countries recently. 80% of patients suffered persistent fev...

Knowledge, attitudes, and practices against the growing threat of COVID-19 among medical students of Pakistan

Of the 1474 medical students in the study, 576 were males, and 898 were females. Two-thirds of the participants 1057(71.7%) had adequate knowledge, an...

Body mass index and outcome in patients with COVID-19: A dose-response meta-analysis

A total of 34,390 patients from 12 studies were included in this meta-analysis. Increased BMI was associated with increased poor outcomes in patients...

Clinical Outcomes and Plasma Concentrations of Baloxavir Marboxil and Favipiravir in COVID-19 Patients: An Exploratory Randomized, Controlled Trial

Favipiravir and baloxavir acid were evaluated for their antiviral activity against SARS-CoV-2 before the trial. One reason for the lack of virological...

Transmissibility of COVID-19 depends on the viral load around onset in adult and symptomatic patients

High viral loads around onset may contribute to the secondary transmission of COVID-19. The viral load may help provide a better understanding of why...

Obesity Increases the Severity and Mortality of Influenza and COVID-19: A Systematic Review and Meta-Analysis

The study compared the impacts of obesity on the severity and mortality of influenza and COVID-19. Obesity was a risk factor for the severity of influ...

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