Efficacy and safety of certolizumab pegol in an unselected crohn's disease population: 26-week data of the FACTS II survey
This prospective phase IV study aimed to evaluate the efficacy and safety. Response and remission rates were 70% and 40% (week 6) and 67% and 36%, res...
The ACCURE-trial: the effect of appendectomy on the clinical course of ulcerative colitis, a randomised international multicenter trial (NTR2883) and the ACCURE-UK trial: a randomised external pilot trial (ISRCTN56523019)
Appendectomy might alter the clinical course of established UC. The objective of this body of research is to evaluate the short-term and medium-term e...
Randomized phase III trial in elderly patients comparing LV5FU2 with or without irinotecan for first-line treatment of metastatic colorectal cancer (FFCD 2001-02)
Four arms were randomly assigned to receive 5-FU (5-fluorouracil)-based CT. No significant difference was observed for the median PFS. Adding irinotec...
Second-line chemotherapy for advanced biliary tract cancer after failure of the gemcitabine-platinum combination: A large multicenter study by the Association des Gastro-Entérologues Oncologues
Few data are available on second-line chemotherapy (CT2) for advanced biliary tract cancer (ABTC) CT2 might provide disease control for selected patie...
Endoscopic mucosal resection (EMR) versus endoscopic submucosal dissection (ESD) for resection of large distal non-pedunculated colorectal adenomas (MATILDA-trial): rationale and design of a multicenter randomized clinical trial
Endoscopic mucosal resection (EMR) is currently the most used technique for the resection of large distal colorectal polyps. We hypothesize that ESD i...
Lanreotide Autogel in the Treatment of Idiopathic Refractory Diarrhea: Results of an Exploratory, Controlled, Before and After, Open-label, Multicenter, Prospective Clinical Trial
Somatostatin analogues have the ability to reduce gastrointestinal secretions and motility. Lanreotide Autogel decreased symptoms and improved quality...
Intravenous cyclosporine for severe attacks of ulcerative colitis: a survey of Canadian gastroenterologists
A single randomized trial evaluated the use of cyclosporine treatment for severe attacks of ulcerative colitis. Over 90% of respondents believe that f...
Objective benefit of a 1-day training course in endoscopic hemostasis using the "compactEASIE" endoscopy simulator
The Erlangen Active Simulator for Interventional Endoscopy (EASIE) was introduced in 1997. Objective evidence of the benefits of training with this mo...
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