Endoscopic mucosal resection (EMR) versus endoscopic submucosal dissection (ESD) for resection of large distal non-pedunculated colorectal adenomas (MATILDA-trial): rationale and design of a multicenter randomized clinical trial
Endoscopic mucosal resection (EMR) is currently the most used technique for the resection of large distal colorectal polyps. We hypothesize that ESD is more time-consuming in the short run, resulting in higher healthcare costs, but is more cost-effective in the long term.

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