Pregnancy and Neonatal Outcomes After Fetal Exposure to Biologics and Thiopurines Among Women With Inflammatory Bowel Disease
Pregnant women with inflammatory bowel disease (IBD) may require biological or thiopurine therapy to control disease activity. Drug exposure did not increase the rate of congenital malformations, spontaneous abortions, preterm birth, low birth weight, or infections during the first year of life. Higher disease activity was associated with a higher risk of spontaneous abortion.
