Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function
The intestinal microbiome affects the prevalence and pathophysiology of a variety of diseases ranging from inflammation to cancer. We aimed to identify disease-relevant phenotypes associated with faecal microbiota (in-)stability. The greatest microbiome instability was associated with factors contributing to metabolic syndrome such as fatty liver disease and diabetes mellitus. Greatest stability of the microbiome was determined by higher initial alpha diversity, female sex and high household inc
