Randomised clinical trial: standard of care versus early-transjugular intrahepatic porto-systemic shunt (TIPSS) in patients with cirrhosis and oesophageal variceal bleeding
Early-transjugular intrahepatic porto-systemic shunt (TIPSS) recommended in international guidelines for high-risk patients with oesophageal variceal bleeding. After one year, 7 patients died in the standard of care group and six in the early-TIPSs group, a 1-year survival of 75.9% vs 79.3% respectively. Serious adverse events were similar in both treatment groups, except rates of hepatic encephalopathy were higher in patients receiving TIPSS.
