Effects of intensive versus standard blood pressure control on domain-specific cognitive function: a substudy of the SPRINT randomised controlled trial
Systolic Blood Pressure Intervention Trial(SPRINT) was an open-label, multicentre, randomized controlled trial. Participants were adults 50 years or older with systolic blood pressure higher than 130 mm Hg. After a median follow-up of 4 years, there was no between-group difference. An intensive treatment to lower systolic blood pressure did not result in a clinically relevant difference compared with standard treatment.

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