Cortical diffusion kurtosis imaging and thalamic volume are associated with cognitive and walking performance in relapsing–remitting multiple sclerosis
In MS, pronounced neurodegeneration manifests itself as cerebral gray matter (GM) atrophy. The study looked at the relationship between morphological and diffusional properties in cerebral GM and physical and cognitive performance in RRMS patients. Thalamic volume was associated with SSST, 6MWT, information processing, global cognitive performance, and volume of WM lesions. Cortical diffusion and thalamic volume are associated with walking and cognitive performance in RRMS patients and are highl