Endothelium-restricted endothelin-1 overexpression in type 1 diabetes worsens atherosclerosis and immune cell infiltration via NOX1

Endothelin (ET)-1 has been implicated in diabetes-induced vascular complications. ET-1 overexpression increased 2.5-fold and five-fold the atheroscler...

Sensory and Motor Axonal Excitability Testing in Early Diabetic Neuropathy

The study aims to gain insight into the pathophysiology of diabetic polyneuropathy. One hundred and eleven types 2 diabetics with and without DPN were...

Fetal descent in nulliparous women assessed by ultrasound: a longitudinal study

Ultrasound measurements offer objective and reproducible methods to measure the fetal head station. This study aimed to use ultrasound measurements to...

Grand challenges for medical physics in radiation oncology

Medical physicists are key players in the clinical and scientific radiation oncology context. They have unique skill sets, flexibility, clinical invol...

Peer mentoring: evaluation of a novel programme in paediatrics

Mentoring is a core skill in the UK paediatric postgraduate curriculum. There is a paucity of peer mentoring programmes aimed at postgraduate doctors...

Resource Utilization and Outcomes in Isolated Low-Grade Renal Trauma at a Level 1 Trauma Center

The study examined admission and transfer patterns of isolated low-grade renal trauma given the lack of evidence-based guidelines. All patients were d...

Remote ischaemic preconditioning ameliorates anthracycline-induced cardiotoxicity and preserves mitochondrial integrity

Anthracycline-induced cardiotoxicity (AIC) is a serious adverse effect among cancer patients. The central mechanism of AIC is irreversible mitochondri...

Neuropsychiatric symptoms associated with cerebral small vessel disease: a systematic review and meta-analysis

Cerebral small vessel disease is a common cause of vascular dementia. It is often considered clinically silent before dementia or stroke becomes appar...

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