Forecasting seizure risk in adults with focal epilepsy: a development and validation study

Evidence from studies using chronic EEG (cEEG) revealed that epileptic brain activity shows robust cycles. Forecasts with a shorter horizon of 1 h, po...

The influence of timing of surgical decompression for acute spinal cord injury: a pooled analysis of individual patient data

There is a strong biological rationale for early decompression of the injured spinal cord, but the influence of the timing of surgical decompression f...

Prevalence and correlates of physical activity across kidney disease stages: an observational multicentre study

Physical inactivity is a major modifiable risk factor for morbidity and mortality. The study investigated the prevalence of physical inactivity and de...

Enteropeptidase inhibitor SCO-792 effectively prevents kidney function decline and fibrosis in a rat model of chronic kidney disease

Inhibiting enteropeptidase suppresses food intake and ameliorates obesity and diabetes in mice. The study found a decline in glomerular filtration rat...

The receptor activator of nuclear factor κΒ ligand receptor leucine-rich repeat-containing G-protein-coupled receptor 4 contributes to parathyroid hormone-induced vascular calcification

In chronic kidney disease, serum phosphorus (P) elevations stimulate parathyroid hormone (PTH) production. PTH is the main regulator of the receptor a...

Cardiopulmonary resuscitation (CPR) training strategies in the times of COVID-19: a systematic literature review comparing different training methodologies

Study compared learning outcomes of standard in-person CPR training with alternative methods of training. Trainees in the hybrid group performed bette...

The efficacy and safety of hydroxychloroquine (HCQ) in treatment of COVID19 -a systematic review and meta-analysis

Hydroxychloroquine (HCQ) has been one of the most widely tested drugs for SARS CoV2 on account of its antiviral properties. This systematic review and...

Plants as source of new therapies for endometriosis: a review of preclinical and clinical studies

Given the disadvantages and limitations of current endometriosis therapy, There is a progressive increase in studies focusing on plant-derived agents...

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