Patient-reported wellbeing and clinical disease measures over time captured by multivariate trajectories of disease activity in individuals with juvenile idiopathic arthritis in the UK: a multicentre prospective longitudinal study

Juvenile idiopathic arthritis (JIA) is a heterogeneous disease. Clusters of children and young people might experience different global patterns in th...

Perceived Access to Handguns Among Colorado High School Students

Access to firearms among youth can increase the risk of suicide or other injuries. The 2019 Healthy Kids Colorado Survey was an anonymous survey admin...

Pregnancy and Neonatal Outcomes After Fetal Exposure to Biologics and Thiopurines Among Women With Inflammatory Bowel Disease

Pregnant women with inflammatory bowel disease (IBD) may require biological or thiopurine therapy to control disease activity. Drug exposure did not i...

Longitudinal Changes in Fecal Calprotectin Levels Among Pregnant Women With and Without Inflammatory Bowel Disease and Their Babies

The effect of pregnancy on inflammatory bowel disease (IBD) remains poorly understood. fecal calprotectin (FC) levels were measured at each trimester...

Evaluation of SARS-CoV-2 in Tears of Patients with Moderate to Severe COVID-19

To investigate the presence of SARS-CoV-2 RNA in tears of patients with moderate to severe coronavirus disease 2019 (COVID-19). Tears were collected w...

Dupilumab shows long-term effectiveness in a large cohort of treatment-refractory atopic dermatitis patients in daily practice: 52-Week results from the Dutch BioDay registry

Study to study 52-week effectiveness and safety of dupilumab in adult patients with treatment-refractory atopic dermatitis. Results showed a greater t...

Hand dermatitis in adults referred for patch testing: Analysis of North American Contact Dermatitis Group Data, 2000 to 2016

Hand eczema (HE) is a heterogeneous and burdensome disorder. HE was associated with significantly higher odds of positive patch test reactions.

Genetic and clinical characteristics of treatment-resistant depression using primary care records in two UK cohorts

Treatment-resistant depression is a major contributor to the disability caused by a major depressive disorder (MDD) Primary care electronic health rec...

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