Safety and efficacy of prednisone versus placebo in short-term prevention of episodic cluster headache: a multicentre, double-blind, randomised controlled trial
Prednisone is commonly used for short-term therapy of episodic cluster headaches before preventive medication such as verapamil becomes effective. We...
Transperineal Prostate Biopsy Improves the Detection of Clinically Significant Prostate Cancer among Men on Active Surveillance
Transperineal biopsy associated with an increased likelihood of upgrading to clinically significant prostate cancer. This is likely due to better samp...
Evaluation of Ureteroenteric Anastomotic Strictures after the Introduction of Robot-Assisted Radical Cystectomy with Intracorporeal Urinary Diversion: Results from a Large Tertiary Referral Center
47% of patients developed strictures after a radical cystectomy with intracorporeal urinary diversion. The difference in the incidence of strictures w...
Safety and efficacy of riluzole in patients undergoing decompressive surgery for degenerative cervical myelopathy (CSM-Protect): a multicentre, double-blind, placebo-controlled, randomised, phase 3 trial
Degenerative cervical myelopathy is the most common form of non-traumatic spinal cord injury. This multicentre, double-blind, placebo-controlled, rand...
Selecting Patients with Favorable Risk, Grade Group 2 Prostate Cancer for Active Surveillance—Does Magnetic Resonance Imaging Have a Role?
The National Comprehensive Cancer Network recommends that selected men with grade group 2 prostate cancer be considered for active surveillance. The i...
Comparison of eight prehospital stroke scales to detect intracranial large-vessel occlusion in suspected stroke (PRESTO): a prospective observational study
Prehospital stroke scales have been proposed to select patients with large-vessel occlusion for direct transport. The NIHSS as assessed by a clinician...
Detection of α-synuclein in CSF by RT-QuIC in patients with isolated rapid-eye-movement sleep behaviour disorder: a longitudinal observational study
Isolated rapid-eye-movement (REM) sleep behavior disorder (IRBD) can be part of the prodromal stage of the alpha-synucleinopathies Parkinson's disease...
Safety and efficacy of tilavonemab in progressive supranuclear palsy: a phase 2, randomised, placebo-controlled trial
Tilavonemab (ABBV-8E12) is a monoclonal antibody that binds to the N-terminus of human tau. Progressive supranuclear palsy is a neurodegenerative diso...
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