Long-term follow-up from the ORATORIO trial of ocrelizumab for primary progressive multiple sclerosis: a post-hoc analysis from the ongoing open-label extension of the randomised, placebo-controlled, phase 3 trial
Time to onset of disability progression was confirmed with four measures and time to requiring a wheelchair was also analyzed. At the study end, the p...
Safety and efficacy of MD1003 (high-dose biotin) in patients with progressive multiple sclerosis (SPI2): a randomised, double-blind, placebo-controlled, phase 3 trial
Biotin (MD1003) might enhance neuronal and oligodendrocyte energetics, resulting in improved cell function, repair, or survival. MS-SPI randomised, do...
Safety and efficacy of amantadine, modafinil, and methylphenidate for fatigue in multiple sclerosis: a randomised, placebo-controlled, crossover, double-blind trial
Methylphenidate, modafinil, and amantadine are commonly prescribed medications for alleviating fatigue in multiple sclerosis. Authors: The study did n...
Genetic determinants of survival in progressive supranuclear palsy: a genome-wide association study
The genetic basis of variation in the progression of primary tauopathies has not been determined. We aimed to identify genetic determinants of surviva...
Risk of stroke in relation to degree of asymptomatic carotid stenosis: a population-based cohort study, systematic review, and meta-analysis
There has been no systematic analysis of a stenosis-risk association in cohort studies. The 5-year ipsilateral stroke risk increased with the degree o...
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