MRI Brain Templates of the Male Yucatan Minipig
The pig is growing in popularity as an experimental animal because its gyrencephalic brain is similar to humans. Currently, however, there is a lack o...
The impact of the COVID-19 pandemic on radiotherapy services in England, UK: a population-based study
In 2020, mean weekly radiotherapy courses fell by 19% in April, 6% in May, and 11% in June compared with corresponding months in 2019. The largest red...
Identification of novel risk loci and causal insights for sporadic Creutzfeldt-Jakob disease: a genome-wide association study
Human prion diseases are rare and usually rapidly fatal neurodegenerative disorders. Most common is sporadic Creutzfeldt-Jakob disease (sCJD) Variants...
Neurological disease in adults with Zika and chikungunya virus infection in Northeast Brazil: a prospective observational study
Since 2015, the arthropod-borne viruses (arboviruses) have spread across the Americas causing outbreaks. These outbreaks have been accompanied by incr...
Safety and efficacy of galcanezumab in patients for whom previous migraine preventive medication from two to four categories had failed (CONQUER): a multicentre, randomised, double-blind, placebo-controlled, phase 3b trial
We aimed to assess the safety and efficacy of galcanezumab, an antibody to calcitonin gene-related peptide. The primary endpoint was the overall mean...
Neuropathology of patients with COVID-19 in Germany: a post-mortem case series
It is unclear whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) gains access to the CNS. We investigated the brain tissue of patien...
Monogenic variants in dystonia: an exome-wide sequencing study
Dystonia is a clinically and genetically heterogeneous condition that occurs in isolation or in combination with other movement disorders. We sequence...
Effects of intensive versus standard blood pressure control on domain-specific cognitive function: a substudy of the SPRINT randomised controlled trial
Systolic Blood Pressure Intervention Trial(SPRINT) was an open-label, multicentre, randomized controlled trial. Participants were adults 50 years or o...