Impact of disconnected pancreatic duct on recurrence of fluid collections and new-onset diabetes: do we finally have an answer?

Disconnected pancreatic duct (DPD) is a frequent occurrence in cases with walled-off necrosis (WON) The impact of DPD on recurrence of collection afte...

Long-term instability of the intestinal microbiome is associated with metabolic liver disease, low microbiota diversity, diabetes mellitus and impaired exocrine pancreatic function

The intestinal microbiome affects the prevalence and pathophysiology of a variety of diseases ranging from inflammation to cancer. We aimed to identif...

Neutrophils interact with cholangiocytes to cause cholestatic changes in alcoholic hepatitis

Alcoholic hepatitis (AH) is a common but life-threatening disease with limited treatment options. Neutrophils in contact with bile ducts were quantifi...

Randomized Trial of Focused Ultrasound Subthalamotomy for Parkinson's Disease

Focused ultrasound subthalamotomy in one hemisphere improved motor features of Parkinson's disease in selected patients. Adverse events included speec...

Dipeptidyl Peptidase 4 Inhibition for Prophylaxis of Acute Graft-versus-Host Disease

Dipeptidyl peptidase 4 (DPP-4; also known as CD26), a transmembrane receptor expressed on T cells, has a costimulatory function in activating T cells....

Urgent endoscopic retrograde cholangiopancreatography with sphincterotomy versus conservative treatment in predicted severe acute gallstone pancreatitis (APEC): a multicentre randomised controlled trial

Randomised trial compared urgent ERCP with sphincterotomy versus conservative treatment. The primary endpoint was a composite of mortality or major co...

A systematic review of symptomatic small bowel lipomas of the jejunum and ileum

Small bowel lipomas are rarely encountered benign adipose growths found within the small intestine wall or mesentery. We aim to aid clinical decision-...

Endoscopic Ultrasound-Guided, Percutaneous, and Transjugular Liver Biopsy: A Comparative Systematic Review and Meta-Analysis

Endoscopic ultrasound-guided liver biopsy (EUSLB) has become an attractive alternative. EUSLB appears to be a safe, minimally invasive procedure that...

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