Telomere length and risk of idiopathic pulmonary fibrosis and chronic obstructive pulmonary disease: a mendelian randomisation study
Idiopathic pulmonary fibrosis (IPF) is a fatal lung disease accounting for 1% of UK deaths. Short telomere length is associated with IPF and chronic obstructive pulmonary disease (COPD) There was no evidence to infer that telomeres caused COPD, however. Telomere shortening might be a contributory factor in IPF, suggesting divergent mechanisms in COPD. Investigation of therapies that improve telomere length is warranted.

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